effect of fish oil on serum levels of lipid profile, lipoprotein (a), apolipoprotein a-1 and b, fasting sugar and insulin, and insulinresistance in the elderly residents of kahrizak charity foundation

Authors

حسین فخرزاده

hossein fakhrzadeh tehran university of medical sciences and health services, tehran, iran.دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تهران. تهران، ایران مریم قادرپناهی

maryam ghaderpanahi tehran university of medical sciences and health services, tehran, iran.دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تهران. تهران، ایران فرشاد شریفی

farshad sharifi tehran university of medical sciences and health services, tehran, iran.دانشگاه علوم پزشکی و خدمات بهداشتی درمانی تهران. تهران، ایران احمدعلی اکبری کامرانی

ahmad-ali akbarikamrani university of socialwelfare and rehabilitation sciences, tehran, iranدانشگاه علوم بهزیستی و توانبخشی تهران زهره بادامچی زاده

abstract

objectives: this study was performed to investigate the effect of ω-3 fatty acids on lipid profiles, lipoprotein (a), apolipoprotein a-1 and apolipoprotein b, fasting glucose and insulin, and insulin resistance in a group of iranian elderly subjects. methods & materials: in this clinical trial, 124 elderly residents of the kahrizakcharity foundation, aged 65 and older were divided into two intervention (consumption of 1 gram per day of fish oil) and control (consumption of placebo) groups. blood sampling was done at the baseline and at the end of the study. results: after 6 months, tg and apo a-1 increased significantly (p=0.01 and p=0.02, respectively) and high-density lipoprotein cholesterol decreased significantly in the control group (p=0.009). overall and comparative effects of fish oil were positively significant (p=0.02). conclusion: fish oil intake can be effective in reduction of serumtriglycerides in elderly.

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Effect of Fish Oil on Serum Levels of Lipid Profile, Lipoprotein (a), Apolipoprotein A-1 and B, Fasting Sugar and Insulin, and InsulinResistance in the Elderly Residents of Kahrizak Charity Foundation

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